Product overview
Methyl Beta Cyclodextrin is a methylated derivative with strong inclusion and solubilization performance in both aqueous and lipid-associated systems. It is used in pharmaceutical and biochemical research, transdermal formulation work, flavors, fragrances and cosmetics; substitution distribution and cell-compatibility requirements should be evaluated for the intended use.
Function & Usage
- Bind, Lubricate & Support Dosage Forms
Supports dosage-form processing through binding, lubrication, flow, suspension, taste or texture control according to the selected excipient. Typical uses: Drug and active-ingredient solubilization, Transdermal and formulation research, Flavor and fragrance encapsulation.
- Emulsify & Solubilize Ingredients
Supports emulsification or solubilization of oil, fragrance or other formulation components according to the selected ingredient. Typical uses: Drug and active-ingredient solubilization, Transdermal and formulation research, Flavor and fragrance encapsulation.
- Soothe, Moisturize & Improve Skin Feel
Supports soothing, moisturization, repair or sensorial improvement according to the selected cosmetic ingredient. Typical uses: Drug and active-ingredient solubilization, Transdermal and formulation research, Flavor and fragrance encapsulation.
- Deliver Cooling & Protect Volatile Aroma
Provides cooling or helps disperse, protect and control the delivery of volatile flavor and fragrance ingredients. Typical uses: Drug and active-ingredient solubilization, Transdermal and formulation research, Flavor and fragrance encapsulation.
Specification
| Item | Specifications | COA Result |
|---|---|---|
| Appearance | White powder, Highly soluble in water and methanol, Freely soluble in ethanol and ethylene glycol, Almost insoluble in cyclohexane and ethyl acetate. | Conforms |
| Odor | Odorless | Conforms |
| Taste | Slightly sweet taste | Conforms |
| Assay | ≥98% | 99.80% |
| pH | 5.0-7.5 | 5.61 |
| Clarity of solution | 2.5g/25ml aqueous solution is clear. | Conforms |
| Absorbance of Impurities | 220 - 350 nm: ≤ 1.0. 350 - 750 nm: 50.1. | Conforms |
| Average Substitution Degree | 7.0~13.3 | 11.5 |
| Loss on Drying | ≤7.0% | 1.78% |
| Betadex | ≤0.2% | No ND |
| Residue on Ignition | ≤0.5% | 0.04% |
| Total Plate Count | ≤1000 cfu/g | <10 cfu/g |
| Total Yeast & Mold | ≤100 cfu/g | <10 cfu/g |
| E.Coli. | Negative | Conforms |
| Bacterial endotoxins | ≤10 EU/g | <10 EU/g |
| Total Heavy Metal | ≤10 ppm | <10 ppm |
Product information
- Primary category:
- Pharmaceuticals & Healthcare, Personal Care & Cosmetic, Food & Nutrition
- Subcategory:
- Cyclodextrin Excipients & Solubilizers
- CAS No.:
- 128446-36-6
- Form:
- White powder
- Content / Grade:
- Assay ≥98%; average degree of substitution 7.0-13.3
- Applications:
- Drug and active-ingredient solubilization, Transdermal and formulation research, Flavor and fragrance encapsulation, Cosmetic stabilization and odor masking
- Hazard / Transport:
- Typical supplied grades are not commonly regulated as dangerous goods. Fine dust may irritate the eyes or respiratory tract and can form combustible dust concentrations in air; confirm the current grade-specific SDS and destination-market transport status.
- Storage:
- Keep tightly sealed in a cool, dry and well-ventilated place. Protect from moisture, heat, direct light, contamination and strong odors.