Product overview
Beta Cyclodextrin is the most widely used natural cyclodextrin for inclusion, stabilization, taste or odor masking and controlled release. Its broad cavity fit and established use make it an entry product for pharmaceutical, food, flavor, fragrance and personal-care customers, while grade and regulatory status must be selected for the intended market.
Function & Usage
- Bind, Lubricate & Support Dosage Forms
Supports dosage-form processing through binding, lubrication, flow, suspension, taste or texture control according to the selected excipient. Typical uses: Pharmaceutical excipient and active stabilization, Flavor, fragrance and food-ingredient encapsulation, Odor masking and controlled release.
- Soothe, Moisturize & Improve Skin Feel
Supports soothing, moisturization, repair or sensorial improvement according to the selected cosmetic ingredient. Typical uses: Pharmaceutical excipient and active stabilization, Flavor, fragrance and food-ingredient encapsulation, Odor masking and controlled release.
- Deliver Cooling & Protect Volatile Aroma
Provides cooling or helps disperse, protect and control the delivery of volatile flavor and fragrance ingredients. Typical uses: Pharmaceutical excipient and active stabilization, Flavor, fragrance and food-ingredient encapsulation, Odor masking and controlled release.
Specification
Chinese Pharmacopoeia 2020
| Item | Specifications | COA Result |
|---|---|---|
| Appearance(25 °C) | White, crystalline or crystalline powder, slightly soluble in water, almost insoluble in methanol, ethanol or acetone. | Conforms |
| Assy, % | 98.0~102.0 | 99.70% |
| Specific Rotation [α] d 20 | +160o~+164o | +161.6o |
| Identification - Chemical | Generate a yellow-brown precipitate | Conforms |
| Identification - HPLC | The retention time of the main peak of the test solution should be consistent with that of the main peak of the reference solution. | Conforms |
| Identification - IR | The infrared absorption spectrum of this product should be consistent with that of the reference substance. | Conforms |
| pH | 5.0-8.0 | 6.3 |
| The Clarity and Color of the Solution | I t should be clear and colorless; i f it appears turbid, it should be compared with the No. 2 turbidity standard solution and must not be more concentrated | Conforms |
| Absorbance of Impurities | 220-350 nm:≤0.10 350-750 nm:≤0.05 | Conforms |
| Chloride | ≤0.018% | <0.018% |
| Reducing Sugar | ≤ 0.5% | <0.5% |
| Residual Solvent - Cyclohexane | ≤ 0.388% | <0.388% |
| Residual Solvent - Trichloroethylene | ≤0.001% | <0.001% |
| Residual Solvent - Toluene | ≤ 0.001% | <0.001% |
| Related Substance - Alpha Cyclodextrin | ≤0.25% | <0.25% |
| Related Substance - Gamma Cyclodextrin | ≤ 0.25% | <0.25% |
| Related Substance - Various Impurities | ≤ 0.5% | <0.5% |
| Loss on Drying | ≤ 14.0% | 9.90% |
| Residue on Ignition | ≤ 0.1% | 0.02% |
| Heavy Metal | ≤ 5ppm | <0.0005% |
| Arsenic Salt | ≤0.0002% | <0.0002% |
| Microbial Limit - Total Aerobic Bacteria Count | ≤ 1000 cfu/g | < 10 cfu/g |
| Microbial Limit - Total Count of Molds and Yeasts | ≤ 100 cfu/g | < 10 cfu/g |
| Microbial Limit - Escherichia Coli | Absent | Negative |
EP 11.0
| Item | Specifications | COA Result |
|---|---|---|
| Appearance(25 °C) | White or almost white crystalline powder. | Conforms |
| Solubility | Freely soluble in water, almost insoluble in ethanol. | Conforms |
| Assy(on a dry basis), % | 98.0~102.0 | 99.93% |
| Specific Rotation [α] d 20 | +160o~+164o | +161.6o |
| Infrared Spectrometry | The infrared absorption spectrum of this product should be consistent with that of the reference substance. | Conforms |
| pH | 5.0-8.0 | 6.3 |
| The Clarity and Color of the Solution | I t should be clear and colorless; i f it appears turbid, it should be compared with the No. 2 turbidity standard solution and must not be more concentrated | Conforms |
| Absorbance of Impurities | 230-350 nm:≤0.10 350-750 nm:≤0.05 | Conforms |
| Chloride | ≤0.01% | <0.01% |
| Sulphate | ≤0.01% | <0.01% |
| Reducing Sugar | ≤ 0.5% | <0.5% |
| Related Substance - Alpha Cyclodextrin | ≤0.25% | <0.25% |
| Related Substance - Gamma Cyclodextrin | ≤ 0.5% | <0.5% |
| Related Substance - Other Impurities | ≤ 0.5% | <0.5% |
| Loss on Drying | ≤ 14.0% | 9.90% |
| Residue on Ignition | ≤ 0.1% | 0.02% |
| Heavy Metal | ≤ 10ppm | < 10 ppm |
| Arsenic Salt | ≤0.0002% | <0.0002% |
| Microbial Limit - Total Aerobic Bacteria Count | ≤ 1000 cfu/g | < 10 cfu/g |
| Microbial Limit - Total Count of Molds and Yeasts | ≤ 100 cfu/g | < 10 cfu/g |
| Microbial Limit - Escherichia Coli | Absent | Negative |
Product information
- Primary category:
- Pharmaceuticals & Healthcare, Food & Nutrition, Personal Care & Cosmetic
- Subcategory:
- Natural Cyclodextrins & Encapsulation Agents
- CAS No.:
- 7585-39-9
- Form:
- White crystalline powder
- Content / Grade:
- Assay 98-102%; pharmaceutical, food or enterprise grade by specification
- Applications:
- Pharmaceutical excipient and active stabilization, Flavor, fragrance and food-ingredient encapsulation, Odor masking and controlled release, Separation and host-guest chemistry
- Hazard / Transport:
- Typical supplied grades are not commonly regulated as dangerous goods. Fine dust may irritate the eyes or respiratory tract and can form combustible dust concentrations in air; confirm the current grade-specific SDS and destination-market transport status.
- Storage:
- Keep tightly sealed in a cool, dry and well-ventilated place. Protect from moisture, heat, direct light, contamination and strong odors.